Folic Acid is synthetically produced, and used in fortified foods and supplements because it can be converted into Folate in the body. To be used, it must be converted to tetrahydrofolate (tetrahydrofolic acid). Increasing evidence suggests that this process may be slow in humans, especially people with a particular genetic mutation (more on that shortly). Conversely, folates occur naturally in many foods and are especially plentiful in dark green leafy vegetables, and they work directly in the body. Our Quatrefolic® is already in a biologically active form, so it can be efficiently utilized even by people who have the gene mutation.*

Some people have a genetic mutation, or polymorphism, that hinders their body from efficiently converting dietary or supplemental Folate to its usable form, methylfolate. If you test positive for MTFHR, the solution is for your Folate supplement to be in the active form so your body does not have to convert it – called L-methylfolate.*

The human body needs Folate to methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in supporting cell division and supporting normal energy-yielding metabolism.*

Folic Acid is a water-soluble vitamin. It dissolves in water and is not stored in your fat cells. This means that you need to keep taking Folate as your body cannot develop a reserve. And unfortunately, there are a lot of ways people can fall short.*

There are big variations in how efficiently Folic Acid and Folate is converted to the bioactive form in different people due to the MTHFR call-out I mentioned. Quatrefolic® bypasses the MTHFR conversion step and delivers a "finished" Folate the body can efficiently use at the cellular level.*